Reglan/Risperdal/Seroquel and Tardive Dyskinesia
Tardive dyskinesia ("TD") is characterized by involuntary and repetitive movements of the body including: lip smacking, grimacing, tongue protrusion, rapid eye movements or blinking, puckering, impaired movement of the fingers, and tremors. It often develops after taking medications that contain metoclopramide, which block dopamine receptors. These often irreversible symptoms may lessen or resolve after metoclopramide treatment is stopped. Still, some people can get so bad it's hard for them to eat and swallow because of their tongue movements, and others experience tremors for years and years, even after use of the medication is discontinued.
One of the medications most often linked to TD is Reglan, and at the end of February, 2009, the FDA ordered that a "black box" warning highlighting the risk of TD and other serious neurological side effects be placed on all drugs that contain metoclopramide, including Reglan. Reglan is prescribed to treat various gastrointenstinal disorders, including but not limited to the slow stomach emptying that can occur in tandem with diabetes. Reglan has also been pushed on doctors as a second-line treatment for heartburn stemming from gastroesophageal reflux. Although the FDA has long been aware of the risk of TD when dopamine blockers such as Reglan are used, apparently the drug is still being prescribed for longer periods of time than the 4-12 week recommendation, which only further increases the likelihood of developing TD, an untreatable disorder with life-altering, sometimes permanent, symptoms.
Additionally, the medications Risperdal and Seroquel have been linked to the development of TD. These medications are among several atypical antipsychotics, often referred to as neuroleptics and prescribed for the treatment of psychosis, including schizophrenia. In addition to TD, these drugs can cause many severe adverse effects, including suicide, and diabetes.
According to studies, TD develops in 10-20% of patients using these drugs for several years and estimates claim over 1 million Americans could be affected. This muscle disorder can be permanent and risk increases the longer you are treated. Those at greatest risk include the elderly, especially older women, and people who have been on the drug for a long time.
If you or a loved one has taken Reglan, Risperdal, Seroquel, or any other drug containing metoclopramide and been diagnosed with tardive dyskinesia, please contact us for an free consultation. Pogust Braslow & Millrood LLC works tirelessly to protect the rights of consumers affected by the pharmaceutical industry and is at the forefront of many such litigations throughout the country.
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